Health

Enduring multiple surgeries to set complex bone fractures with steel or titanium screws and plates may soon be a thing of the past. New bioceramic bone screws compatible with the body's own bone material and shaped to decrease injury to bones and tendons are being introduced by Fraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM.

 The beginning of ski season is a hectic time for alpine emergency centers when injuries to the neck, knee, pelvis and hips (including hip fractures in mature skiers) are common occurrences. Those with complex bone fractures will undergo surgery to set then with titanium or steel screws and plates. But because these metal screws and plates can cause inflammation and allergies in sensitive people when left in the body, patients must endure considerable discomfort and expense having the metal pieces removed in a second operation after the injury has healed.

 Now a new bioceramic implant screw nail or "scrail", developed by researchers at Fraunhofer IFAM and the university hospitals of Giessen-Marburg and Bonn and the University of Bremen, is primed to turn such injury treatment into history. Walking on the beach is one of the things that is often good for therapy and general health here in in Monterey. Real estate that is close to the water of often sought out by those who have a frequent walking regimen to enhance mobility and flexibility.

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Early detection of medical conditions is key to proper treatment and management. Unfortunately, because this typically requires tests, often invasive, that are performed in a doctor's office or medical lab, early detection does not happen as often as it should. New technology, however, holds the potential to diagnose diabetes with a simple smartphone-linked breathalyzer. It might be soon that I'll leave my home in Carmel and before I start the day easily check my health by blowing into my phone.

Scientists are currently developing technologies that are capable of analyzing the volatile organic compounds in human breath. Better known as VOCs, these compounds provide insight into what is going on in the human body. In the case of diabetes, an elevated acetone level is a significant biomarker that can indicate a problem. Scientists are developing hand-held devices with adsorbent polymers to capture acetone from human breath and hold it onto it for analysis by a laser. The analysis will be able to show whether someone is diabetic. These non-invasive, portable breathalyzers could someday be the first line of defense for spotting diabetes in patients. 

The first use of such technology would probably be in medical offices. Yes, means that early detection would still be dependent on making an appointment with...

It is estimated that approximately 100 million people in the United States suffer from some type of chronic pain. This chronic pain not only diminishes their quality of life, but it can also lead to feelings of despair and depression; often destroying relationships as well as a person’s sense of well-being. There can be many reasons for chronic pain, but there’s no denying that it is a condition that needs to be treated with some type of pain therapy. Unfortunately, not only is managing pain with traditional pain medications extremely expensive, it can often lead to addiction or even an overdose. Today, we live in a society where many people are addicted to pain medications. Suffering in pain is certainly not the answer, but is there a healthier solution to managing this debilitating pain?

Everyone from veterans to housewives, and adolescents are turning to opioids as a way to get relief from chronic pain. Fortunately, new research conducted at the University of Arizona has shown that a safer, healthier and non-pharmacological approach to pain management is possible. This new approach to pain management involves the use of green light emitting diodes or LEDs.

While pain treatment with greed LED light has certainly shown promise as a pain management tool, it also might be a great solution to helping resolve opioid addiction rates in the U.S. From residents in Pacific Grove homes to New York City homeowners, finding a healthier way to treat pain while lowering the risk of addiction is definitely something that could prove extremely beneficial for many people.

It is estimated that treating chronic pain in the U.S. has risen to approximately $635 billion a year. That’s an incredible figure, one...

Although some researchers feel a moral obligation to cure genetic diseases with DNA editing techniques such as CRISPR, others hesitate to embark on gene editing of human eggs, sperm and early-stage embryos(called germline editing) whose DNA changes can be passed on to future descendants. These practitioners feel that not enough is understood, and further research is critical for exploring the early development of embryos and fetuses. Such research would resurrect ethical questions about creating and destroying viable or non-viable fetuses, and the creation or termination of human life.

One example of a lethal inheritable genetic disease, potentially curable through gene-editing, is Huntington's disease, caused by a gene defect that will trigger a fatal brain condition even in someone with just a single copy of the gene. Gene editing could remove the defect from an egg cell to prevent the disease from being passed on to descendants. Some laboratories are working now, trying to edit egg stem cells to rid them of inherited genetic disease. The end-to-end process is multi-step, and would no doubt first be worked out in animals such as cattle, pigs, and rabbits.

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If you suffer from Alzheimer's or know that a loved one is struggling with the condition, it's important to note that new scientific breakthroughs may provide the public with key insights regarding the disease. Learn more about the efforts of researchers and how their findings could revolutionize the approach to curing the disease by reviewing the following outline:

Beta-Amyloid And Alzheimer's Disease: A Brief Overview

To fully understand the scientific breakthroughs that have transpired in the field of Alzheimer's research, one must first grasp the relevance of beta-amyloid within this sector. As Lund University's researchers understand, toxic clumps of beta-amyloid are believed to be the root cause of Alzheimer's. In the past, researchers thought that beta-amyloid should be eliminated. However, new findings indicate that the protein should be stabilized. 

The History Of Beta-Amyloid

For quite some time, members of the scientific community have thought that beta-amyloid appeared almost immediately in cases of Alzheimer's. It is for this reason that the phrase "popcorn plaques" was coined. Now, however, infrared spectroscopy images reveal information that contradicts this basic assumption. Specifically, researchers are now able to note molecular, structural changes that take place in the brain. 

In discussing the images, professor of experimental neurology...

Researchers and medical professionals continue to reinforce the importance of vitamin D intake to ensure proper bone health. But more recent headlines like “More severe heart disease found in patients with vitamin D deficiency”, “Vitamin D Deficiency Associated with Asthma Exacerbation”, and “Childhood Vitamin D Levels Tied to Adult Atherosclerosis” leave little doubt that there is more significance to this vitamin than most people may realize.

What is Vitamin D?

Vitamin D is a fat soluble vitamin that your body can not make on its own; it needs help from nature. That help comes in the form of exposure to natural sunlight. Being fat soluble means your diet must contain some fat if you are trying to get enough vitamin D through your diet alone. It also means you need to have a healthy gut, and be able to eat and digest fat effectively, in order for your body to be able to absorb the fat and the vitamin. This essential vitamin is also necessary for your body to absorb calcium from the foods you eat. Most people are familiar with calcium’s ties to good bone health, but it is also involved in muscle contraction, regulation of body cell growth, reducing and preventing inflammation, and ensuring a healthy immune system. To do all that, this mineral needs vitamin D.

Vitamin D and Your Heart

Your heart is only a part of the cardiovascular system, the system that keeps healthy blood circulating throughout...

kettlebellGet a grip, Californians---A killer kettlebell workout in Pacific Grove burns fat and sculpts sexy muscles! Plus, it improves balance, strength and stability!

Think mini bowling ball with a handle. That best describes what a kettlebell is. And like weight-training with dumbbells, a kettlebell can also be lifted, pushed and pulled during a workout. The difference is in the freedom and versatility of movement.

With a kettlebell class in Pacific Grove, you can row, press, swing and jerk the cast iron equipment in different directions with one or both hands. The heart gets pumping, and it makes for a super aerobics exercise with resistance training. It's a gorgeous, oceanview city whose real estate offers plenty of recreational activities.

A kettlebell workout is great for all ages, including seniors, living in the prime real estate of the Pacific Grove area. And although the equipment might look intimidating, it really isn't. Kettlebells range in weight from 2lbs. to 175lbs. That's quite a huge range, meaning there are many benefits to this exercise at individual abilities.

Of course, instruction using a kettlebell is very important. Exercising with too heavy a kettlebell can cause injury to the spine, neck and so forth. There are a lot of kettlebell classes available across gorgeous ...

Could Pacific Grove home owners someday benefit from new advances in CRISPR gene editing treatment for genetic diseases? 

MIT researchers have recently developed a method of using nanotechnology to deliver CRISPR gene-editing components into mice for treating defective genes in liver cells. Previous CRISPR delivery methods have used viruses that might in some cases elicit possible immune responses from the body. The new study demonstrates for the first time that you can make a nanoparticle that can be used to permanently and specifically edit the DNA in the liver of an adult animal. The success rate for cutting certain genes in 80% of liver cell using this new delivery system was about 80 percent, the best ever attained with CRISPR in adult animals. 

Daniel Anderson, associate professor of chemical engineering at MIT, and member of the MIT Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science is senior author of the study on the Pcsk9 gene which regulates cholesterol levels. He reports that mutations of the Pcsk9 gene in humans is associated with a rare disease called familial hypercholesterolemia. This disorder is treated with antibody drugs that inhibit the Pcsk9 gene and which must be taken on a regular basis for the patient's entire life. Using the new nanoparticle method, the faulty gene is permanently edited in one treatment. Furthermore,...

In Monterey, your mask can be fashionable and express your personality. Take a deep breath before you begin. Basic knowledge of your sewing machine is necessary for this project. For all seams always remember to backstitch at the start and finish of each seam. You will have options for securing the mask to your face with elastic or shoelaces. You will need thread, material, scissors, two 7 inch pieces of elastic or four 15 inch shoelace pieces, an iron and sewing machine. A six-inch piece of pipe cleaner is optional. If you use round elastic, you will need to tie a knot on each end to keep it in place once sewn in. The material can be anything breathable.

Decide on the fabric you want to use. Some can be quite fashionable while some others can actually be quite helpful in filtering out aerosols of the covid -19 particles. Use one layer of tightly woven cotton with 2 layers of polyester spandex material. A sheer fabric like you see on evening gowns can also be used. This combination is likely to provide performance close to the hard to find N-95 mask. You can also use silk or flannel on the inner lining as well. A good quality cotton fabric, the type used for quilting, with a polyester liner is also is great. 

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University of Illinois Chicago is one of the U.S. sites participating in clinical trials to cure severe red blood congenital diseases such as sickle cell anemia or Thalassemia by safely modifying the DNA of patients' blood cells.

The first cases treated with this approach were recently published in an article co-authored by Dr. Damiano Rondelli, the Michael Reese Professor of Hematology at the UIC College of Medicine. The article reports two patients have been cured of beta thalassemia and sickle cell disease after their own genes were edited with CRISPR-Cas9 technology. The two researchers who invented this technology received the Nobel Prize in Chemistry in 2020.

In the paper published in the New England Journal of Medicine, CRISPR-Cas9 Gene Editing for Sickle Cell Disease and beta-Thalassemia, researchers reported gene editing modified the DNA of stem cells by deleting the gene BCL11A, the gene responsible for suppressing fetal hemoglobin production. By doing so, stem cells start producing fetal hemoglobin so that patients with congenital hemoglobin defects (beta thalassemia or sickle cell disease) make enough fetal hemoglobin to overcome the effect of the defective hemoglobin that causes their disease.

The advantage of this approach is that it uses the patient's cells with no need for a donor. Also, the gene manipulation does not use a viral vector as with other gene therapy studies but is done with electroporation (quick production of...

Study shows speeding up roll-out, prioritizing 60-plus could save 65,000 US lives in three months.

Vaccinating older adults for COVID-19 first will save substantially more U.S. lives than prioritizing other age groups, and the slower the vaccine rollout and more widespread the virus, the more critical it is to bring them to the front of the line.

That's one key takeaway from a new University of Colorado Boulder paper, published today in the journal Science, which uses mathematical modeling to make projections about how different distribution strategies would play out in countries around the globe.

The research has already informed policy recommendations by the Centers for Disease Control and the World Health Organization to prioritize older adults after medical workers.

Now, as policymakers decide how and whether to carry out that advice, the paper -- which includes an interactive tool (https://vaxfirst.colorado.edu/) -- presents the numbers behind the tough decision.

"Common sense would suggest you want to protect the older, most vulnerable people in the population first. But common sense also suggests you want to first protect front-line essential workers (like grocery store clerks and teachers) who are at higher risk of exposure," said senior author Daniel Larremore, a computational biologist in the Department of Computer Science and CU Boulder's BioFrontiers Institute. "When common sense leads you in two different directions, math can help you decide."

For the study, Larremore and lead author Kate Bubar, a graduate student in the Department of Applied Mathematics, teamed up with colleagues at the Harvard T.H. Chan School...

Homemade masks help combat the spread of viruses like COVID-19. Researchers tested the breathability and droplet-blocking ability of 11 common household fabrics, using a medical mask as a benchmark. 

Studies indicate that homemade masks help combat the spread of viruses like COVID-19 when combined with frequent hand-washing and physical distancing. Many of these studies focus on the transfer of tiny aerosol particles; however, researchers say that speaking, coughing and sneezing generates larger droplets that carry virus particles. Because of this, mechanical engineer Taher Saif said the established knowledge may not be enough to determine the effectiveness of some fabrics used in homemade masks.

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Skin cancer is a major health concern around the world. Millions are diagnosed with one of the various types of skin cancer each year. Most skin cancers are treatable, but melanoma is a very dangerous type of skin cancer that can spread to other parts of the body. The spread of melanoma may lead to death.

There are three major types of skin cancer. Melanoma is the most dangerous. Melanomas often develop from an existing mole on a person's skin. Squamous cell carcinoma is another common type of skin cancer. This type can spread across the skin and into the mucous membranes. Basal cell carcinoma usually develops on the exposed areas of the body. These skin cancers rarely spread, but they may become large and unsightly.

Doctors know that the main cause of skin cancer is exposure to UV radiation such as that produced by the sun. In order to prevent skin cancer from developing, doctors highly recommend that anyone who is going out in the sun for a prolonged period of time wear sunscreen and that they reapply the sunscreen regularly throughout the day. People who have very fair skin should cover up as much as possible to avoid a sunburn which can lead to skin cancer development.

While these are quite well-known means of preventing skin cancer, researchers have now developed a new way to help beat skin cancer that lets people know their level of UV radiation exposure. Researchers at RMIT University in Melbourne Australia along with a research team at the University of Granada have developed a bracelet that people can use when they go out in the sun.

This bracelet is made up of four emoticon faces. The faces are made of UV sensitive invisible...