If you suffer from Alzheimer's or know that a loved one is struggling with the condition, it's important to note that new scientific breakthroughs may provide the public with key insights regarding the disease. Learn more about the efforts of researchers and how their findings could revolutionize the approach to curing the disease by reviewing the following outline:

Beta-Amyloid And Alzheimer's Disease: A Brief Overview

To fully understand the scientific breakthroughs that have transpired in the field of Alzheimer's research, one must first grasp the relevance of beta-amyloid within this sector. As Lund University's researchers understand, toxic clumps of beta-amyloid are believed to be the root cause of Alzheimer's. In the past, researchers thought that beta-amyloid should be eliminated. However, new findings indicate that the protein should be stabilized. 

The History Of Beta-Amyloid

For quite some time, members of the scientific community have thought that beta-amyloid appeared almost immediately in cases of Alzheimer's. It is for this reason that the phrase "popcorn plaques" was coined. Now, however, infrared spectroscopy images reveal information that contradicts this basic assumption. Specifically, researchers are now able to note molecular, structural changes that take place in the brain. 

In discussing the images, professor of experimental neurology...

Carmel Valley is an incredibly beautiful area with unique terrain. The terrain is one of the appeals of living here, but it also means that Carmel Valley homes for sale are often on steep hills or otherwise face potential access challenges created by the terrain itself. 

However, there is a solution. New research shows that glulam timber bridges can last between 75 and 90 years under ordinary use at the relatively low traffic levels you are likely to see on county and township roads in parts of Carmel Valley. 

These are bridges built from glulam, an engineered wood product that combines wood strips with glue to create a superior structural component compared to unmodified wood timbers. They are also cost effective. 

The research was conducted at J. Lohr Structures Lab. They calculated the typical load and stress tested the bridge to simulate use over a long time frame. The amount of stress incidents the structure survived suggests that such bridges can last for decades.

The bridge they tested was donated by Gruen-Wald Engineered Laminates of Tea. The U.S. Department of Transportation and the South Dakota Department of Transportation worked together as co-sponsors. 

Such bridges take less time to build than other alternatives. This is beneficial to the community by keeping road closures to a minimum. As we've seen with Big Sur fires or the slide that took out the Pfeiffer Canyon Bridge, getting a community back and thriving depend, on speed and cost. For smaller roads and private residences these glulam bridges may one day have their day.

This type of bridge also fits in well with the aesthetic of ...

Carmel or Carmel-by-the-Sea is basically the same place. This city in Monterey California was founded in 1902 and incorporated in 1916 situated on the Monterey Peninsula. This 1 mi.² village is as unique in charm as it is fun and entertaining residents. One fun fact is that unwilling to see their village become too engulfed in the city culture, Carmel's founding fathers rejected the practice of house to house mail delivery in favor of a central post office. And to this day, there are still no addresses, parking meters, street lights, or sidewalks outside of Carmel's downtown commercial area. You're likely to hear neighbors call out directions such as it's the second house on the right past the driftwood fence and so forth.

Often referred to as simply Carmel, there are still a few neighborhoods that are becoming quite popular or have fluctuated with the ebb and flow of today's society. If you're considering a move to Carmel, here are some of the top five neighborhoods for 2021.

Carmel Point

Located just south of downtown, technically outside of the city limits, this beautiful small peninsula offers unobstructed views of Carmel Bay, the Peninsula up along the Pebble Beach and south to Point Lobos and Pine Ridge. This community features the Carmel River elementary school, a few bed and breakfasts, inns and Mara Beach Carmel. You won't find any fussy homeowner association dues or major restrictions but all these homes are already built out so if you're looking to customize a property on Carmel Point, you'll probably have to find an older home that needs a major renovation. Properties on Carmel point offer stunning views, especially those...

Carmel Homes for Sale Market Report June 2020

19 homes were sold in Carmel in June 2020, which is 280% up from 5 sales the month before.

More Market Homes Data in Santa Cruz

Many people do not consider the roofs over their heads until calamity strikes and water is coming through the ceiling. A replacement roof, installed in a timely fashion, is vital for a home's wellbeing and value. Whether the inhabitants are considering selling or simply wanting a safe, dry environment in which to live for years to come, the roof is an essential consideration when it comes to upkeep.

Signs a Roof Needs Replacing

The first place to check, when looking to see if a roof needs replacement, is looking at it from the street. If you see curling or missing shingles, shiny edges, then the next place to check is in the attic. Check for light entering in beams through the house's top. Stains and streaks on the wood in your attic can also signal a leaky roof. Also if you notice brown stains on your ceiling inside your home that could be a sign as well, and you might notice something is amiss there first. The next place to check is a home's improvement records. These may be found at the city or county building department. Different roof types last varying lengths of time; check to see that, for example, it has not been 20-25 years since an asphalt shingle roof has been installed or reshingled.

Replacement Options for Pitched Roofs

Asphalt Shingles

The most common of America's roofing materials, asphalt shingles are effective in every environmental condition. Because of the wide variety in the quality of shingles, check...

Amazing Scenery at Your Front Door

Scenic Road in Carmel-by-the-Sea is a stretch of road that runs from Ocean Avenue to just past the intersection of 17th Avenue and Valley View Avenue. The road winds down the coast along Carmel Beach and offers breathtaking views of the dazzling blue ocean on one side and unique and quirky million dollar homes on the inland side. Traveling down Scenic Road is an interesting stroll that presents a myriad of things to see and experience in a wholly accessible manner.

The ocean side is easy to explore because of the walkways that lead down to the beach, which makes traveling back and forth from the road to the beach a breeze. Sea lions, otters, whales, dolphins and different varieties of birds are just some of the sea life you may observe in the ocean or on points of land while you walk along the road. The beach offers a variety of terrain such as small rock pools, white sand, cypress trees and large rock formations.

Charming and Interesting Homes All Around

If you want to explore the amazing homes that are further inland, just walk down any of the streets that branch off Scenic Road. These streets will then take you into the neighborhoods of the Golden Rectangle. Homes in Carmel in this coveted...

A few years ago you may have researched Carmel homes for sale and ultimately purchased the perfect family home in which to raise a family. Those children are now grown and have moved away, perhaps even owning homes in Carmel of their own and starting their own families. It’s time now to downsize your living space in to a more suitable home, that will ultimately make life easier for you as you grow older.

Purchasing a new home at any time is a serious business and a serious financial investment. Your needs are different now, so this new purchase needs some different thought and considerations. There are a number of things you need to consider when purchasing another home in Carmel that will suit your lifestyle, and needs, in your later years.

Space

A large house with lots of square footage, a large backyard, and many bedrooms and extra bathrooms was perfect for a growing family. All that room was great for outdoor barbeques, birthday parties, and family fun nights but once the kids move out a big house, can feel like a very empty one (but one that still needs to be heated and cleaned). Determine how much space you really need to feel comfortable and allowing for the grand kids to stay over and at some point maybe an in home caretaker.

Lifestyle / Health

You started a family, raised them the best to your ability, and now they have left the family home. As your...

When shopping for a new home, aside from price, one of the biggest decisions involves choosing the type. If you’re considering a Santa Cruz condominium or townhome, here is what you need to know to help you decide if either will be a proper fit.

Definition of a Condo

A condominium, commonly referred to as a condo, is similar to an apartment, though constructed differently: It is one unit in a building that has many co-owners. The difference is that you own a condo but rent an apartment. However, a Santa Cruz condominium is normally situated on a single level and that can range from ground floor to multi-stories high with lovely views. Some oceanview condominiums are highly desired.

Condo Advantages

One of the biggest advantages of moving into a Santa Cruz condo is that you won’t have to worry about any exterior maintenance repairs or maintenance issues because they will be handled by the ( HOA ) home owners association. Depending on the condo, you can also have some of the utility bills included in the fee. That’s because the association often covers part of them. Dependingon location, many amenities such as fitness centers, pools, tennis courts, and security services are considerations of your choice....

If you are planning to buy a home in Carmel, CA, you will want to make sure that any property you wish to invest in is thoroughly inspected. A home inspection can be conducted to check for structural damage and other factors that might influence your decision to purchase. Whether you choose to perform the inspection yourself or hire a professional home inspector, here are a few of the main things that should be inspected when checking out a property.

Roof Quality

The roof should be carefully inspected to look for things like missing tiles or cracks that might allow water to leak into the home. If the roof is severely damaged or outdated, you may need to invest a considerable amount of money in repairs if you wish to purchase that particular property.

Pest Damage

Pests can cause extensive damage to homes, and sometimes this damage is not easily seen right away unless the property is thoroughly inspected. Rats, mice, squirrels and other rodents can chew through wires and cause major damage to the electrical system. Termites can eat away at the wood and cause significant structural damage. A home inspection will also help to identify the presence of bed bugs, wasps and other potentially hazardous creatures.

Plumbing

The state of the pipes, fixtures and other plumbing system components can greatly affect the overall quality of the home. You will want to make sure that every part of the plumbing system is up to standard and that there are no cracks or other signs of damage that could lead to major problems. You may even...

Using Technology to Help Children with Math Has Big Benefits

If you grew up in a Carmel home and went to a typical California school, odds are you have memories of how boring math class was. It's no secret -- surveys show that roughly 40% of Americans find the subject dull or intimidating. Luckily for today's kids, new advances in technology have demonstrable benefits when it comes to helping them engage with the material.

Part of the problem that children face stems from parental help, or a lack thereof. Many parents are reluctant to sit down and work with their children on their math homework. While your average parents with a Carmel home understand the importance of teaching language skills and reading to children frequently, most parents regard teaching subjects like math as a school's duty. Increasing parental engagement alone isn't the answer, however, as a recent study from the University of Chicago found that receiving frequent help from parents who weren't confident in math actually undermined children's performance.

Luckily for those families, a subsequent study may have found the answer -- an iPad app. Bedtime Math is an app that offers children and parents math problems to solve in the context of a bedtime story. It makes the material fun and engaging for children who are anxious or apathetic about math, and provides structure to help prevent math-anxious parents from getting in their children's way.

During the course of the study, the experimental group used Bedtime Math while a control group used a similar bedtime story app without...